Estradiol cypionate, 17 beta-cyclopentylpropinate ester of estradiol (ab145745)

Overview

  • Product name

    Estradiol cypionate, 17 beta-cyclopentylpropinate ester of estradiol
  • Description

    17 β-cyclopentylpropinate ester of estradiol
  • Alternative names

    • Depo-estradiol
    • Depoestradiol
    • Depofemin
    • ECP
    • Estradep
    • estradiol cipionate
    • Estrapo
    see all
  • Biological description

    Synthetic ester of the natural estrogen, estradiol. Acts as a long-acting, intramuscular injectable prodrug of estradiol. Inhibits Endothelin-1 (ET-1) synthesis via estrogen receptor.

  • Purity

    > 99%
  • CAS Number

    313-06-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(8R,9S,13S,14S,17S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-cyclopentylpropanoate
  • Molecular weight

    396.56
  • Molecular formula

    C26H36O3
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Stevenson JS  et al. Use of estradiol cypionate as a substitute for GnRH in protocols for synchronizing ovulation in dairy cattle. J Dairy Sci 87:3298-305 (2004). Read more (PubMed: 15377609) »
  • Overton MW  et al. Evaluation of effect of estradiol cypionate administered prophylactically to postparturient dairy cows at high risk for metritis. J Am Vet Med Assoc 223:846-51 (2003). Read more (PubMed: 14507103) »
  • Dubey RK  et al. Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Hypertension 37:640-4 (2001). Read more (PubMed: 11230349) »
  • Oriowo MA  et al. A comparison of the pharmacokinetic properties of three estradiol esters. Contraception 21:415-24 (1980). Read more (PubMed: 7389356) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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