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Signal Transduction Signaling Pathway Nuclear Signaling Nuclear Hormone Receptors Estrogen
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Anti-Estrogen Inducible Protein pS2 antibody (ab150578)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Estrogen Inducible Protein pS2 antibody (ab150578)

    Key features and details

    • Rabbit polyclonal to Estrogen Inducible Protein pS2
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

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    Recombinant Human Estrogen Inducible Protein pS2 (ab89485)

    View more associated products

    Overview

    • Product name

      Anti-Estrogen Inducible Protein pS2 antibody
      See all Estrogen Inducible Protein pS2 primary antibodies
    • Description

      Rabbit polyclonal to Estrogen Inducible Protein pS2
    • Host species

      Rabbit
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
    • Immunogen

      Recombinant purified Human Estrogen Inducible Protein pS2 (NP_003216.1).

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      pH: 7.20
      Preservative: 0.01% Thimerosal (merthiolate)
      Constituents: 69% PBS, 30% Glycerol, 0.5% BSA
    • Concentration information loading...
    • Purity

      Protein A purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Estrogen

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Recombinant Protein

      • Recombinant Human Estrogen Inducible Protein pS2 (ab89485)
    • Related Products

      • Recombinant Human Estrogen Inducible Protein pS2 (ab89485)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab150578 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
    • Tissue specificity

      Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).
    • Sequence similarities

      Contains 1 P-type (trefoil) domain.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P04155 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 7031 Human
      • Omim: 113710 Human
      • SwissProt: P04155 Human
      • Unigene: 162807 Human
      • Alternative names

        • BCEI antibody
        • Breast cancer estrogen inducible protein antibody
        • Breast cancer estrogen inducible sequence antibody
        • Breast cancer estrogen-inducible protein antibody
        • D21S21 antibody
        • Gastrointestinal trefoil protein antibody
        • Gastrointestinal trefoil protein pS2 antibody
        • hP1.A antibody
        • HP1A antibody
        • HPS 2 antibody
        • HPS2 antibody
        • pNR 2 antibody
        • PNR-2 antibody
        • pNR2 antibody
        • Polypeptide P1.A antibody
        • Protein pS2 antibody
        • PS 2 antibody
        • pS2 antibody
        • pS2 protein antibody
        • TFF 1 antibody
        • TFF1 antibody
        • TFF1_HUMAN antibody
        • Trefoil factor 1 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Estrogen Inducible Protein pS2 antibody (ab150578)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Estrogen Inducible Protein pS2 antibody (ab150578)
        Immunohistochemical analysis of formalin-fixed, paraffin embedded Human colon (goblet cells) tissue labeling Estrogen Inducible Protein pS2 with ab150578 at 5µg/ml.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (0)

      Publishing research using ab150578? Please let us know so that we can cite the reference in this datasheet.

      ab150578 has not yet been referenced specifically in any publications.

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