Overview

  • Product name

    Anti-Estrogen Inducible Protein pS2 antibody [SPM313] - BSA and Azide free
    See all Estrogen Inducible Protein pS2 primary antibodies
  • Description

    Mouse monoclonal [SPM313] to Estrogen Inducible Protein pS2 - BSA and Azide free
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-P, Flow Cyt, ICC/IFmore details
  • Species reactivity

    Reacts with: Human, Cynomolgus monkey
  • Immunogen

    Synthetic peptide corresponding to Human Estrogen Inducible Protein pS2 aa 57-84 (C terminal).
    Sequence:

    CFDDTVRGVPWCFYPNTIDVPPEEECEF


    Database link: P04155

  • Positive control

    • Human ovarian carcinoma tissue; Normal stomach tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: 100% PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    ab212861 is purified from Bioreactor Concentrate by Protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    SPM313
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab212861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

(Primary incubation for 30 minutes at RT).

Flow Cyt Use 0.5-1µg for 106 cells.

(in 0.1 ml).

ICC/IF Use a concentration of 0.5 - 1 µg/ml.

Target

  • Function

    Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
  • Tissue specificity

    Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).
  • Sequence similarities

    Contains 1 P-type (trefoil) domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • BCEI antibody
    • Breast cancer estrogen inducible protein antibody
    • Breast cancer estrogen inducible sequence antibody
    • Breast cancer estrogen-inducible protein antibody
    • D21S21 antibody
    • Gastrointestinal trefoil protein antibody
    • Gastrointestinal trefoil protein pS2 antibody
    • hP1.A antibody
    • HP1A antibody
    • HPS 2 antibody
    • HPS2 antibody
    • pNR 2 antibody
    • PNR-2 antibody
    • pNR2 antibody
    • Polypeptide P1.A antibody
    • Protein pS2 antibody
    • PS 2 antibody
    • pS2 antibody
    • pS2 protein antibody
    • TFF 1 antibody
    • TFF1 antibody
    • TFF1_HUMAN antibody
    • Trefoil factor 1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human ovarian carcinoma tissue labeling Human Estrogen Inducible Protein pS2 with ab212861 at 1µg/ml.

References

ab212861 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab212861.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up