Anti-Estrogen Related Receptor gamma antibody (ab171816)
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Overview
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Product nameAnti-Estrogen Related Receptor gamma antibody
See all Estrogen Related Receptor gamma primary antibodies -
DescriptionMouse polyclonal to Estrogen Related Receptor gamma
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Orangutan
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Immunogen
Full length protein corresponding to Human Estrogen Related Receptor gamma aa 1-435. Mature Estrogen Related Receptor gamma
Sequence:MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMN GHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSM PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEIT KRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLN PQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLAD RELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIA LANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPL LRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
Database link: NP_996317.1 -
Positive control
- Estrogen Related Receptor gamma-transfected 293T cell line lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.2
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab171816 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. |
Target
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FunctionOrphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.
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Tissue specificityExpressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
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Sequence similaritiesBelongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Developmental stageExpressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
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Post-translational
modificationsSumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. -
Cellular localizationNucleus.
- Information by UniProt
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Database links
- Entrez Gene: 2104 Human
- Entrez Gene: 26381 Mouse
- Entrez Gene: 360896 Rat
- Omim: 602969 Human
- SwissProt: P62508 Human
- SwissProt: P62509 Mouse
- SwissProt: P62510 Rat
- Unigene: 444225 Human
see all -
Alternative names
- DKFZp781L1617 antibody
- ERR 3 antibody
- ERR G2 antibody
see all
Images
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Western blot - Anti-Estrogen Related Receptor gamma antibody (ab171816)All lanes : Anti-Estrogen Related Receptor gamma antibody (ab171816) at 1 µg/ml
Lane 1 : Estrogen Related Receptor gamma-transfected 293T cell line lysate
Lane 2 : Non-transfected lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 49 kDa
Protocols
Datasheets and documents
References
ab171816 has not yet been referenced specifically in any publications.
