Anti-Estrogen Related Receptor gamma antibody - N-terminal (ab150539)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Estrogen Related Receptor gamma antibody - N-terminal
See all Estrogen Related Receptor gamma primary antibodies -
Description
Rabbit polyclonal to Estrogen Related Receptor gamma - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except ESRRB (64%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Cow, Dog, Turkey, Xenopus laevis, Lizard, Monkey, Zebrafish, Gorilla, Opossum, Common marmoset, Orangutan, Bat, Platypus, Elephant
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Immunogen
Synthetic 14 amino acid peptide from the N terminus of Human Estrogen Related Receptor gamma.
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Positive control
- Human small intestine tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab150539 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. -
Tissue specificity
Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland. -
Sequence similarities
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Developmental stage
Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver. -
Post-translational
modificationsSumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 421357 Chicken
- Entrez Gene: 536732 Cow
- Entrez Gene: 478961 Dog
- Entrez Gene: 101837462 Hamster
- Entrez Gene: 100050530 Horse
- Entrez Gene: 2104 Human
- Entrez Gene: 26381 Mouse
- Entrez Gene: 100355568 Rabbit
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Alternative names
- DKFZp781L1617 antibody
- ERR 3 antibody
- ERR G2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Estrogen Related Receptor gamma antibody - N-terminal (ab150539)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human small intestine tissue labelling Estrogen Related Receptor gamma with ab150539 at 5µg/ml.
Protocols
References
ab150539 has not yet been referenced specifically in any publications.
