Overview

  • Product name

    Estrone, Estrogenic hormone
  • Description

    Estrogenic hormone
  • Biological description

    Estrogenic hormone. Shows carcinogenic and neuroprotective effects in vivo.
  • Purity

    > 97%
  • CAS Number

    53-16-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (8R,9S,13S,14S)-3-Hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
  • Molecular weight

    270.37
  • Molecular formula

    C18H22O2
  • PubChem identifier

    5870
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Gatson JW  et al. Estrone is neuroprotective in rats after traumatic brain injury. J Neurotrauma 29:2209-19 (2012). Read more (PubMed: 22435710) »
  • Al-Ansari AM  et al. The development of an optimized sample preparation for trace level detection of 17a-ethinylestradiol and estrone in whole fish tissue. J Chromatogr B Analyt Technol Biomed Life Sci 879:3649-52 (2011). Read more (PubMed: 21982913) »
  • Raeside JI & Christie HL Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. Biochem Biophys Res Commun 401:469-72 (2010). Read more (PubMed: 20875396) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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