Overview

  • Product name

    Ethidium bromide, fluorescent dye for DNA/RNA staining
  • Description

    Intercalating fluorescent dye reagent for DNA/RNA staining
  • Alternative names

    • 3,8-Diamino-5-ethyl-6-phenylphenanthridinium bromide
    • Dromilac
    • EtBr
    • Homidium bromide
  • Biological description

    Intercalates double-stranded DNA and RNA. Bound Ethidium bromide fluoresces very strongly compared to free Ethidium bromide. Commonly used reagent for use in gel staining and other staining purposes. Acts as a frameshift mutagen and is a DNA polymerase inhibitor because of its ability to bind to DNA.

  • Purity

    > 99%
  • CAS Number

    1239-45-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Diaz F  et al. Human mitochondrial DNA with large deletions repopulates organelles faster than full-length genomes under relaxed copy number control. Nucleic Acids Res 30:4626-33 (2002). Read more (PubMed: 12409452) »
  • Sigmon J & Larcom LL The effect of ethidium bromide on mobility of DNA fragments in agarose gel electrophoresis. Electrophoresis 17:1524-7 (1996). Read more (PubMed: 8957173) »
  • Stevenson P  et al. Comparison of isometamidium chloride and homidium bromide as prophylactic drugs for trypanosomiasis in cattle at Nguruman, Kenya. Acta Trop 59:77-84 (1995). Read more (PubMed: 7676909) »
  • Scaria PV & Shafer RH Binding of ethidium bromide to a DNA triple helix. Evidence for intercalation. J Biol Chem 266:5417-23 (1991). Read more (PubMed: 2005088) »
  • LePecq JB & Paoletti C A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization. J Mol Biol 27:87-106 (1967). Read more (PubMed: 6033613) »
  • Elliott WH The effects of antimicrobial agents on deoxyribonucleic acid polymerase. Biochem J 86:562-7 (1963). Read more (PubMed: 16748992) »
See 1 Publication for this product

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