Overview

  • Product name

    Ethinyl Estradiol, estrogen receptor agonist
  • Description

    Potent estrogen receptor agonist
  • Purity

    > 99%
  • CAS Number

    57-63-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (8R,9S,13S,14S,17R)-17-Ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
  • Molecular weight

    296.40
  • Molecular formula

    C20H24O2
  • PubChem identifier

    5591
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=C(C=C2C(=C1)[C@]3([C@@](CC2)([C@]4([C@](CC3)([C@@](CC4)(O)C#C)C)[H])[H])[H])O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Overgaard A  et al. The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus. Neurotoxicology 37:154-62 (2013). Read more (PubMed: 23660487) »
  • Unkila M  et al. Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause. J Steroid Biochem Mol Biol 138:107-15 (2013). Read more (PubMed: 23665515) »
  • Sonneveld E  et al. Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicol Sci 83:136-48 (2005). Read more (PubMed: 15483189) »

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