Etoposide, Topoisomerase II inhibitor (ab120227)
- Datasheet
- References (2)
Overview
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Product nameEtoposide, Topoisomerase II inhibitor
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DescriptionTopoisomerase II inhibitor
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Biological descriptionTopoisomerase II inhibitor. Anticancer agent.
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Purity> 98%
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CAS Number33419-42-0
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Chemical structure
Properties
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Chemical name4'-Demethylepipodophyllotoxin-9-(4,6-O-ethylidene-β-D-glucopyranoside)
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Molecular weight588.56
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Molecular formulaC29H32O13
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Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
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Solubility overviewSoluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILESCOc1cc(cc(OC)c1O)[C@@H]5c2cc7OCOc7cc2[C@@H](O[C@@H]3OC4CO[C@@H](C)O[C@H]4[C@H](O)[C@H]3O)[C@H]6COC(=O)[C@H]56
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Source
Synthetic
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Research areas
References
This product has been referenced in:
- Baldwin EL & Osheroff N Etoposide, topoisomerase II and cancer. Curr Med Chem Anticancer Agents 5:363-72 (2005). Read more (PubMed: 16101488) »
- Hande KR Etoposide: four decades of development of a topoisomerase II inhibitor. Eur J Cancer 34:1514-21 (1998). Read more (PubMed: 9893622) »
