Key features and details
- Topoisomerase II inhibitor
- CAS Number: 33419-42-0
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameEtoposide, Topoisomerase II inhibitor
DescriptionTopoisomerase II inhibitor
Topoisomerase II inhibitor. Anticancer agent.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120227 has been referenced in 8 publications.
- Hu Q et al. The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks. Cell Rep 30:1235-1245.e4 (2020). PubMed: 31995761
- Sola M et al. Tau affects P53 function and cell fate during the DNA damage response. Commun Biol 3:245 (2020). PubMed: 32427887
- Sultana S & Bishayi B Etoposide-mediated depletion of peripheral blood monocytes post s.aureus infection attenuates septic arthritis by modulating macrophage-derived factors responsible for inflammatory destruction. Immunol Lett 220:51-62 (2020). PubMed: 32032616
- Hijaze N et al. Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors. J Leukoc Biol N/A:N/A (2020). PubMed: 33205451
- Lammert CR et al. AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment. Nature 580:647-652 (2020). PubMed: 32350463
- Tian R et al. CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons. Neuron 104:239-255.e12 (2019). PubMed: 31422865
- Ulrich G et al. Phosphorylation of nuclear Tau is modulated by distinct cellular pathways. Sci Rep 8:17702 (2018). PubMed: 30531974
- Saliou B et al. Development and in vitro evaluation of a novel lipid nanocapsule formulation of etoposide. Eur J Pharm Sci 50:172-80 (2013). PubMed: 23831519