Overview

  • Product name

    Evans blue, L-glutamate uptake inhibitor
  • Description

    Potent inhibitor of L-glutamate uptake
  • Biological description

    Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.

    Also available in simple stock solutions (ab146727) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity

    > 95%
  • CAS Number

    314-13-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Emanueli C  et al. Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. Hypertension 31:1299-304 (1998). Read more (PubMed: 9622145) »
  • Price CJ & Raymond LA Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate receptors and modulates receptor desensitization. Mol Pharmacol 50:1665-71 (1996). Read more (PubMed: 8967991) »
See 1 Publication for this product

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