Evans blue (mM/ml), L-glutamate uptake inhibitor (ab146727)
Key features and details
- Potent inhibitor of L-glutamate uptake. 1 ml water soluble pack.
- CAS Number: 314-13-6
- Purity: > 95%
- Soluble in 1 ml water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Evans blue (mM/ml), L-glutamate uptake inhibitor -
Description
Potent inhibitor of L-glutamate uptake. 1 ml water soluble pack. -
Biological description
Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more. -
Purity
> 95% -
CAS Number
314-13-6 -
Chemical structure
Properties
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Chemical name
6,6'-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid] tetrasodium salt -
Molecular weight
960.80 -
Molecular formula
C34H24N6Na4O14S4 -
PubChem identifier
9566057 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 ml water to give specified mM/ml concentration -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(O[Na])c6cc(c(N)c5c6ccc(/N=N/c1ccc(cc1C)c4ccc(/N=N/c3ccc2c(cc(c(N)c2c3O)S(=O)(=O)O[Na])S(=O)(=O)O[Na])c(C)c4)c5O)S(=O)(=O)O[Na] -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab146727 has not yet been referenced specifically in any publications.