Overview

  • Product name

    Exendin-4 (Exenatide),  GLP-1 receptor agonist
  • Description

    Potent GLP-1 receptor agonist
  • Alternative names

    • AC 2993
    • Exenatide
  • Biological description

    High affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM).
  • Purity

    > 95%
  • CAS Number

    141758-74-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Thorens B  et al. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 42:1678-82 (1993). Read more (PubMed: 8405712) »
  • Malhotra R  et al. Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini. Regul Pept 41:149-56 (1992). Read more (PubMed: 1279756) »
  • Eng J  et al. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 267:7402-5 (1992). Read more (PubMed: 1313797) »

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