Overview

  • Product name

  • Description

    Rabbit polyclonal to EXOC7
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 74 and 345 of EXOC7 (NP_001013861; UniProt ID: Q9UPT5 isoform 1).

  • Positive control

    • WB: HeLa whole cell lysate; H1299, HepG2 and MOLT4 cell lysates ICC/IF: A431 cell

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 78 kDa.
ICC/IF 1/100 - 1/200.

Target

  • Function

    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion.
  • Sequence similarities

    Belongs to the EXO70 family.
  • Domain

    The N-terminus is involved in SEC8 and ARHQ binding.
    The C-terminus is required for translocation to the plasma membrane.
  • Cellular localization

    Cytoplasm > cytosol. Cell membrane. Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2 5 3p antibody
    • DKFZp686J04253 antibody
    • EX070 antibody
    • EXO70 antibody
    • Exo70p antibody
    • EXOC 1 antibody
    • EXOC 7 antibody
    • EXOC1 antibody
    • Exoc7 antibody
    • EXOC7_HUMAN antibody
    • Exocyst complex component 7 antibody
    • Exocyst complex component Exo70 antibody
    • FLJ40965 antibody
    • FLJ46415 antibody
    • KIAA1067 antibody
    • Rexo70 antibody
    • YJL085W antibody
    see all

Images

  • Anti-EXOC7 antibody (ab95981) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 78 kDa



    7.5% SDS PAGE
  • Immunofluorescence analysis of paraformaldehyde-fixed A431, using ab95981 at 1/200 dilution. Lower image merged with DNA probe.

References

This product has been referenced in:

  • Arasaki K  et al. Legionella remodels the plasma membrane-derived vacuole by utilizing exocyst components as tethers. J Cell Biol 217:3863-3872 (2018). Read more (PubMed: 30275106) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab95981.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up