Anti-EXOSC3 antibody (ab104161)
Key features and details
- Rabbit polyclonal to EXOSC3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-EXOSC3 antibody
See all EXOSC3 primary antibodies -
Description
Rabbit polyclonal to EXOSC3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-168 of Human EXOSC3 (AAH02437).
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Positive control
- A431, Jurkat and Raji whole cell lysates; 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab104161 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 30 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 30 kDa. |
Target
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Relevance
EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. It is required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. [Swiss-Prot] -
Cellular localization
Cytoplasm. Nucleus, nucleolus. -
Database links
- Entrez Gene: 533245 Cow
- Entrez Gene: 51010 Human
- Entrez Gene: 66362 Mouse
- Omim: 606489 Human
- SwissProt: Q3T0E1 Cow
- SwissProt: Q9NQT5 Human
- SwissProt: Q7TQK4 Mouse
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Alternative names
- bA3J10.7 antibody
- CGI 102 antibody
- CGI-102 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab104161 has been referenced in 1 publication.
- Haas G et al. Identification of factors involved in target RNA-directed microRNA degradation. Nucleic Acids Res 44:2873-87 (2016). WB ; Human . PubMed: 26809675