• Product name
    Anti-Ezrin / Radixin / Moesin antibody
    See all Ezrin / Radixin / Moesin primary antibodies
  • Description
    Rabbit polyclonal to Ezrin / Radixin / Moesin
  • Host species
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region near the C terminus of Human Ezrin/ Radixin/ Moesin.

  • Positive control
    • Human Breast tissue and Mouse NIH-3T3 cells.



Our Abpromise guarantee covers the use of ab118572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 68 kDa.
ELISA 1/20000.
IHC-P Use a concentration of 10 µg/ml.


  • Relevance
    Ezrin is a cytoplasmic peripheral membrane protein and functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
  • Cellular localization
    Cell Membrane, Cytoskeleton and Cytoplasmic
  • Database links
  • Alternative names
    • CVIL antibody
    • CVL antibody
    • Cytovillin 2 antibody
    • Cytovillin antibody
    • Deafness autosomal recessive 24 antibody
    • DFNB24 antibody
    • DKFZp762H157 antibody
    • EZR antibody
    • FLJ26216 antibody
    • Membrane organizing extension spike protein antibody
    • MGC1584 antibody
    • MSN antibody
    • OTTHUMP00000017506 antibody
    • OTTHUMP00000017507 antibody
    • OTTHUMP00000023438 antibody
    • p81 antibody
    • RDX antibody
    • VIL2 antibody
    • Villin 2 antibody
    • Villin 2 ezrin antibody
    • Villin2 antibody
    see all


  • ab118572, at 10 µg/ml, staining Ezrin / Radixin / Moesin in formalin-fixed, paraffin-embedded Human Breast tissue by Immunohistochemistry.
  • All lanes : Anti-Ezrin / Radixin / Moesin antibody (ab118572) at 1/500 dilution

    Lane 1 : NIH-3T3 cell extract without the synthesized peptide.
    Lane 2 : NIH-3T3 cell extract with the synthesized peptide.

    Predicted band size: 68 kDa


ab118572 has not yet been referenced specifically in any publications.

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