Overview

  • Product name

  • Description

    Rabbit polyclonal to F2RL3
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human F2RL3 (C terminal). Synthetic peptide, corresponding to 16 amino acids from the C-terminal region of Human F2RL3.

  • Positive control

    • Human lung and human respiratory epithelium tissue.
  • General notes

    Previously labelled as Proteinase Activated Receptor 4.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab150551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 - 25 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
  • Tissue specificity

    Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Coagulation factor II (thrombin) receptor like 3 antibody
    • Coagulation factor II receptor like 3 antibody
    • Coagulation factor II receptor-like 3 antibody
    • F2RL3 antibody
    • PAR 4 antibody
    • PAR-4 antibody
    • PAR4 antibody
    • PAR4_HUMAN antibody
    • protease activated receptor 4 antibody
    • protease activated receptor4 antibody
    • Proteinase activated receptor 4 antibody
    • Proteinase-activated receptor 4 antibody
    • Thrombin receptor like 3 antibody
    • Thrombin receptor-like 3 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung, respiratory epithelium, tissue, labeling F2RL3 with ab150551 at 10 µg/ml.

References

ab150551 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab150551.
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