Overview

  • Product name

  • Description

    Rabbit polyclonal to FABP-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human FABP-1 aa 174-392.
    Database link: P00505

  • Positive control

    • Recombinant Human FABP-1 protein (ab140064) can be used as a positive control in WB. HepG2, Mouse Neuro2A and Rat lung whole cell lysates; HeLa cells; Human hepatoma, Rat RT2 xenograft and Human SkHep1 xenograft tissues.
  • General notes

    Previously labelled as GOT2. 

Properties

Applications

Our Abpromise guarantee covers the use of ab153924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
  • Sequence similarities

    Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  • Cellular localization

    Mitochondrion matrix. Cell membrane. Exposure to alcohol promotes translocation to the cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • AATM_HUMAN antibody
    • AL022787 antibody
    • Aspartate aminotransferase 2 antibody
    • Aspartate aminotransferase antibody
    • Aspartate aminotransferase, mitochondrial antibody
    • Aspartate transaminase 2 antibody
    • ASPATA antibody
    • EC 2.6.1.1 antibody
    • FABP 1 antibody
    • FABP pm antibody
    • FABP-1 antibody
    • FABPpm antibody
    • Fatty acid binding protein antibody
    • Fatty acid-binding protein antibody
    • FLJ40994 antibody
    • Glutamate oxaloacetate transaminase 2 antibody
    • Glutamate oxaloacetate transaminase 2, mitochondrial antibody
    • Glutamate oxaloacetate transaminase, mitochondrial antibody
    • Glutamic oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) antibody
    • Got 2 antibody
    • GOT2 antibody
    • KAT4 antibody
    • KATIV antibody
    • kynurenine aminotransferase 4 antibody
    • Kynurenine aminotransferase IV antibody
    • kynurenine--oxoglutarate transaminase 4 antibody
    • kynurenine--oxoglutarate transaminase IV antibody
    • mAspAT antibody
    • MGC102129 antibody
    • MGC115763 antibody
    • mitAAT antibody
    • mitochondrial antibody
    • Mitochondrial aspartate aminotransferase antibody
    • OTTMUSP00000017748 antibody
    • Plasma membrane fatty acid binding protein antibody
    • Plasma membrane-associated fatty acid-binding protein antibody
    • Transaminase A antibody
    see all

Images

  • Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 48 kDa



    10% SDS PAGE
  • Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + Mouse Neuro2A whole cell lysate at 30 µg

    Predicted band size: 48 kDa



    10 % SDS-PAGE
  • Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + Rat lung lysate at 50 µg

    Predicted band size: 48 kDa



    10 % SDS-PAGE
  • Immunofluorescence analysis of methanol-fixed HeLa cells, labeling FABP-1 with ab153924 at 1/500 dilution. Lower image shows cells co-stained with Hoechst 33342.

  • Immunohistochemical analysis of paraffin-embedded Rat RT2 xenograft tissue, labeling FABP-1 with ab153924 at 1/500 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human SKHep1 xenograft tissue, labeling FABP-1 with ab153924 at 1/500 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, labeling FABP-1 with ab153924 at 1/500 dilution.

References

This product has been referenced in:

  • Du F  et al. SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis. Cell Death Dis 10:239 (2019). Read more (PubMed: 30858360) »
See 1 Publication for this product

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