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Cardiovascular Lipids / Lipoproteins Fatty Acids Binding proteins
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Anti-FABP5 antibody [FABP5/3750] (ab268056)

  • Datasheet
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP5 antibody [FABP5/3750] (ab268056)
  • Protein Array - Anti-FABP5 antibody [FABP5/3750] (ab268056)

Key features and details

  • Mouse monoclonal [FABP5/3750] to FABP5
  • Suitable for: IHC-P, Protein Array
  • Reacts with: Human
  • Isotype: IgG2a

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Secondary
Product image
Goat Anti-Mouse IgG H&L (HRP) (ab205719)

View more associated products

Overview

  • Product name

    Anti-FABP5 antibody [FABP5/3750]
    See all FABP5 primary antibodies
  • Description

    Mouse monoclonal [FABP5/3750] to FABP5
  • Host species

    Mouse
  • Tested Applications & Species

    Application Species
    IHC-P
    Human
    See all applications and species data
  • Immunogen

    Recombinant full length protein within Human FABP5 aa 1-135. The exact sequence is proprietary.
    Database link: Q01469

  • Positive control

    • IHC-P: Human liver tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    Purified from Bioreactor concentrate
  • Clonality

    Monoclonal
  • Clone number

    FABP5/3750
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Fatty Acids
    • Binding proteins
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cardiovascular
    • Lipids / Lipoproteins
    • Fatty Acids
    • Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Fatty acids
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Fatty acid oxidation
    • Cardiovascular
    • Angiogenesis
    • Endothelial Cell Markers

Associated products

  • Alternative Versions

    • Anti-FABP5 antibody [FABP5/3750] - BSA and Azide free (ab268177)
  • Compatible Secondaries

    • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
    • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab268056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-P
Human
Application Abreviews Notes
IHC-P
Use a concentration of 0.1 - 0.2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Protein Array
Use at an assay dependent concentration.
Notes
IHC-P
Use a concentration of 0.1 - 0.2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Protein Array
Use at an assay dependent concentration.

Target

  • Function

    High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
  • Tissue specificity

    Keratinocytes; highly expressed in psoriatic skin.
  • Sequence similarities

    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • Domain

    Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localization

    Cytoplasm.
  • Target information above from: UniProt accession Q01469 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 2171 Human
    • Omim: 605168 Human
    • SwissProt: Q01469 Human
    • Unigene: 408061 Human
    • Alternative names

      • CFABP antibody
      • Cutaneous fatty acid binding protein antibody
      • DA11 antibody
      • Differentiation associated lipid binding protein LP2 antibody
      • E-FABP antibody
      • EFABP antibody
      • Epidermal-type fatty acid-binding protein antibody
      • FABP5 antibody
      • FABP5_HUMAN antibody
      • fatty acid binding protein 5 (psoriasis-associated) antibody
      • Fatty acid binding protein epidermal antibody
      • Fatty acid-binding protein 5 antibody
      • Fatty acid-binding protein, epidermal antibody
      • Keratinocyte lipid binding protein antibody
      • KFABP antibody
      • Klbp antibody
      • mal1 antibody
      • PA-FABP antibody
      • PAFABP antibody
      • Psoriasis associated fatty acid binding protein homolog antibody
      • Psoriasis-associated fatty acid-binding protein homolog antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP5 antibody [FABP5/3750] (ab268056)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP5 antibody [FABP5/3750] (ab268056)

      Formalin-fixed, paraffin-embedded human liver tissue stained for FABP5 using ab268056 at 0.2 ug/ml in immunohistochemical analysis.

    • Protein Array - Anti-FABP5 antibody [FABP5/3750] (ab268056)
      Protein Array - Anti-FABP5 antibody [FABP5/3750] (ab268056)

      Protein Array containing more than 19,000 full-length human proteins using ab268056. Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab268056? Please let us know so that we can cite the reference in this datasheet.

    ab268056 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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