Overview

  • Product name

  • Description

    Rabbit polyclonal to FABP6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, ELISA, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat
  • Immunogen

    Recombinant ileal fatty acid binding protein

Properties

Applications

Our Abpromise guarantee covers the use of ab91184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
ELISA Use at an assay dependent concentration.
WB 1/50. Predicted molecular weight: 14 kDa.
IHC-P 1/50.

Target

  • Function

    Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • Tissue specificity

    Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • Sequence similarities

    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • Domain

    Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localization

    Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • Fabp6 antibody
    • FABP6_HUMAN antibody
    • Fatty acid binding protein 6, ileal (gastrotropin) antibody
    • Fatty acid-binding protein 6 antibody
    • Gastrotropin antibody
    • GT antibody
    • I 15P antibody
    • I BABP antibody
    • I BALB antibody
    • I BAP antibody
    • I-15P antibody
    • I-BABP antibody
    • I15P antibody
    • IBABP antibody
    • IBALB antibody
    • IBAP antibody
    • ILBP antibody
    • ILBP3 antibody
    • Ileal lipid binding protein antibody
    • Ileal lipid-binding protein antibody
    • ILLBP antibody
    • Intestinal 15 kDa protein antibody
    • Intestinal bile acid binding protein antibody
    • Intestinal bile acid-binding protein antibody
    see all

References

This product has been referenced in:

  • Ferrebee CB  et al. Organic Solute Transporter a-ß Protects Ileal Enterocytes From Bile Acid-Induced Injury. Cell Mol Gastroenterol Hepatol 5:499-522 (2018). Read more (PubMed: 29930976) »
See 1 Publication for this product

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