Overview

  • Product name

    Anti-Factor D/CFD antibody [D10/4]
    See all Factor D/CFD primary antibodies
  • Description

    Mouse monoclonal [D10/4] to Factor D/CFD
  • Host species

    Mouse
  • Specificity

    ab121054 is specific for complement Factor D/CFD in Human serum and plasma.

  • Tested applications

    Suitable for: Sandwich ELISA, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human Factor D/CFD.

  • General notes

     This product was previously labelled as Factor D

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.1% Sodium azide
    Constituents: 97% Phosphate Buffer, 2.9% Sodium chloride
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    D10/4
  • Myeloma

    x63-Ag8.653
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA 1/250. as capture antibody. The dilution guideline for ELISA is based on sandwich ELISA in combination with a polyclonal antibody against the antigen.
WB Use at an assay dependent concentration. Use under non reducing condition. Predicted molecular weight: 27 kDa.

Target

  • Function

    Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
  • Involvement in disease

    Defects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease.
  • Sequence similarities

    Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Adipsin antibody
    • Adipsin/complement factor D antibody
    • Adn antibody
    • C3 convertase activator antibody
    • CFAD_HUMAN antibody
    • CFD antibody
    • Complement factor D antibody
    • complement factor D preproprotein antibody
    • D component of complement antibody
    • DF antibody
    • FactorD antibody
    • PFD antibody
    • Properdin factor D antibody
    see all

References

ab121054 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab121054.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up