Question (46653) | Anti-Factor X + Xa antibody [MM0192-10A10] (ab89334)

Go to datasheet (ab89334)

Question

To whom it may concern,
Do you have any epitope compatibility information regarding the two Abs below?
Factor X + Xa antibody (ab89334)
Factor Xa Heavy Chain antibody (ab75180)
Thanks in advance.
Best Regards

Answer

Thank you for contacting us.

The immunogen of ab75180 corresponds to the amino acid sequence between 235-488 (Swiss-port No. P00742). This sequence corresponds to the factor Xa chain of coagulation factor X. This ab will not recognize uncleaved (inactive) Factor X; will only recognize active Factor Xa.

The ab89334 immunogen was a full length uncleaved human factor X protein. This antibody will recognize both factor X (heavy and light chain) and factor Xa.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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