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To whom it may concern,
Do you have any epitope compatibility information regarding the two Abs below?
Factor X + Xa antibody (ab89334)
Factor Xa Heavy Chain antibody (ab75180)
Thanks in advance.
Asked on May 09 2012
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The immunogen of ab75180 corresponds to the amino acid sequence between 235-488 (Swiss-port No. P00742). This sequence corresponds to the factor Xa chain of coagulation factor X. This ab will not recognize uncleaved (inactive) Factor X; will only recognize active Factor Xa.
The ab89334 immunogen was a full length uncleaved human factor X protein. This antibody will recognize both factor X (heavy and light chain) and factor Xa.
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Answered on May 09 2012