• Product name

    Anti-Factor XIII/XIIIa antibody
  • Description

    Rabbit polyclonal to Factor XIII/XIIIa
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to A-subunit of human coagulation Factor XIII.

  • Positive control

    • Capillary hemangioma, dermatofibroma and placenta.



Our Abpromise guarantee covers the use of ab45000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 160 kDa (un-reduced dimer) or 80kDa (reduced monomer).
IHC-P 1/2000.


  • Relevance

    Factor XIII is a beta globulin found in plasma and is composed of two subunits. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Factor XIII A is the catalytic subunit and is a dimmer of molecular weight 160kDa. The B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIII A, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
  • Cellular localization

    Cytoplasmic in most tissues, but also secreted in the blood plasma
  • Database links

  • Alternative names

    • Coagulation factor XIII A chain antibody
    • Coagulation factor XIII A chain precursor antibody
    • Coagulation factor XIII A polypeptide antibody
    • Coagulation factor XIII A1 polypeptide antibody
    • Coagulation factor XIII A1 subunit antibody
    • Coagulation factor XIIIa antibody
    • F13A antibody
    • F13A1 antibody
    • Factor XIIIA antibody
    • FXIIIA antibody
    • Protein glutamine gamma glutamyltransferase A chain antibody
    • TGase antibody
    • Transglutaminase A chain antibody
    see all


ab45000 has not yet been referenced specifically in any publications.

Customer reviews and Q&As


Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement with the order number xxx with ab1834.

To check the status of the order please contact our Customer Service team and reference this number.

Please note that this free of charge replacement vial is also covered by our Abpromise guarantee. Should you still be experiencing difficulties, or if you have any further questions, please do not hesitate to let us know.

I wish you the best of luck with your research.

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