Key features and details
- FAK autophosphorylation inhibitor. 1 ml water soluble pack.
- CAS Number: 4506-66-5
- Soluble in 1ml of water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Product nameFAK Inhibitor 14 (mM/ml), FAK autophosphorylation inhibitor
DescriptionFAK autophosphorylation inhibitor. 1 ml water soluble pack.
Selective focal adhesion kinase (FAK) autophosphorylation inhibitor (IC50 = 1 μM). No significant activity at other kinases including EGFR, PDGFR and IGF-RI. Increases cell detachment and inhibits cell adhesion in cancer cells. Anticancer agent. Active in vivo and in vitro.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
Chemical name1,2,4,5-Benzenetetramine tetrahydrochloride
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 1ml of water to give specified mM/ml concentration
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146739 has been referenced in 1 publication.
- Sun C et al. Osteopontin-Enhanced Autophagy Attenuates Early Brain Injury via FAK-ERK Pathway and Improves Long-Term Outcome after Subarachnoid Hemorrhage in Rats. Cells 8:N/A (2019). PubMed: 31461955