• Product name

    Anti-FAM120A/OSSA antibody
    See all FAM120A/OSSA primary antibodies
  • Description

    Rabbit polyclonal to FAM120A/OSSA
  • Host species

  • Specificity

    ab106454 will not cross-react with FAM120B / PGCC1.
  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human FAM120A/OSSA (internal sequence).
    Database link: NP_055427

  • Positive control

    • SK-N-SH cell lysate; Rat brain tissue.
  • General notes

     This product was previously labelled as FAM120A




Our Abpromise guarantee covers the use of ab106454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa.
IHC-P Use at an assay dependent concentration.


  • Function

    May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
  • Tissue specificity

    Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
  • Sequence similarities

    Belongs to the constitutive coactivator of PPAR-gamma family.
  • Post-translational

    Arg-982 is dimethylated, probably to asymmetric dimethylarginine.
    Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure.
  • Cellular localization

    Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure.
  • Information by UniProt
  • Database links

  • Alternative names

    • C9orf10 antibody
    • Chromosome 9 open reading frame 10 antibody
    • Constitutive coactivator of PPAR gamma like protein 1 antibody
    • Constitutive coactivator of PPAR-gamma-like protein 1 antibody
    • DNA polymerase transactivated protein 5 antibody
    • DNA polymerase transactivated protein 1 antibody
    • DNAPTP1 antibody
    • DNAPTP5 antibody
    • F120A_HUMAN antibody
    • FAM120A antibody
    • Family with sequence similarity 120A antibody
    • Hypothetical protein LOC23196 antibody
    • KIAA0183 antibody
    • LOC23196 antibody
    • MGC111527 antibody
    • MGC133257 antibody
    • OSSA antibody
    • Oxidative stress-associated Src activator antibody
    • Protein FAM120A antibody
    see all


  • Lane 1 : Anti-FAM120A/OSSA antibody (ab106454) at 0.5 µg/ml
    Lane 2 : Anti-FAM120A/OSSA antibody (ab106454) at 1 µg/ml

    All lanes : SK-N-SH cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 122 kDa

  • ab106454, at 2.5µg/ml, staining FAM120A/OSSA in Rat brain tissue by Immunohistochemistry.

  • Immunofluorescence of FAM120A/OSSA in Rat Brain cells using ab106454 at 20 ug/ml.


This product has been referenced in:

  • Zheng G  et al. TMEM43-S358L mutation enhances NF-?B-TGFß signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Protein Cell N/A:N/A (2018). Read more (PubMed: 29980933) »
See 1 Publication for this product

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