Key features and details
- Rabbit polyclonal to FAM120A/OSSA
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-FAM120A/OSSA antibody
See all FAM120A/OSSA primary antibodies
DescriptionRabbit polyclonal to FAM120A/OSSA
Specificityab106454 will not cross-react with FAM120B / PGCC1.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human FAM120A/OSSA (internal sequence).
Database link: NP_055427
- SK-N-SH cell lysate; Rat brain tissue.
This product was previously labelled as FAM120A
Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106454 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa.|
|IHC-P||Use at an assay dependent concentration.|
FunctionMay participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Tissue specificityUbiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
Sequence similaritiesBelongs to the constitutive coactivator of PPAR-gamma family.
modificationsArg-982 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure.
Cellular localizationCytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure.
- Information by UniProt
- C9orf10 antibody
- Chromosome 9 open reading frame 10 antibody
- Constitutive coactivator of PPAR gamma like protein 1 antibody
Lane 1 : Anti-FAM120A/OSSA antibody (ab106454) at 0.5 µg/ml
Lane 2 : Anti-FAM120A/OSSA antibody (ab106454) at 1 µg/ml
All lanes : SK-N-SH cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 122 kDa
ab106454, at 2.5µg/ml, staining FAM120A/OSSA in Rat brain tissue by Immunohistochemistry.
Immunofluorescence of FAM120A/OSSA in Rat Brain cells using ab106454 at 20 ug/ml.
ab106454 has been referenced in 1 publication.
- Zheng G et al. TMEM43-S358L mutation enhances NF-?B-TGFß signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Protein Cell N/A:N/A (2018). PubMed: 29980933