Overview

  • Product name

  • Description

    Rabbit polyclonal to FAM20C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 362-411 (CFYGECSYYC STEHALCGKP DQIEGSLAAF LPDLSLAKRK TWRNPWRRSY) human FAM20C (NP_064608).

  • Positive control

    • HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab81128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 64 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Calcium-binding protein which may play a role in dentin mineralization.
  • Tissue specificity

    Widely expressed.
  • Involvement in disease

    Defects in FAM20C are the cause of Raine syndrome (RNS) [MIM:259775]. RNS is an autosomal recessive osteosclerotic bone dysplasia with neonatal lethal outcome. Clinical features include generalized osteosclerosis, craniofacial dysplasia and microcephaly.
  • Sequence similarities

    Belongs to the FAM20 family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C76981 antibody
    • Dentin matrix protein 4 antibody
    • DKFZp547C074 antibody
    • DMP-4 antibody
    • DMP4 antibody
    • DMP4_HUMAN antibody
    • Extracellular serine/threonine protein kinase Fam20C antibody
    • Fam20c antibody
    • Family with sequence similarity 20 member C antibody
    • GEF CK antibody
    • Golgi enriched fraction casein kinase antibody
    • Protein FAM20C antibody
    • RNS antibody
    see all

Images

  • Anti-FAM20C antibody (ab81128) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 64 kDa
    Observed band size: 55 kDa
    why is the actual band size different from the predicted?

References

This product has been referenced in:

See 1 Publication for this product

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