Product nameFAM38A/PIEZO1 peptide
See all FAM38A/PIEZO1 proteins and peptides
Our Abpromise guarantee covers the use of ab133015 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-FAM38A/PIEZO1 antibody (ab128245)
This product was previously labelled as FAM38A
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.12% BSA
- Family with sequence similarity 38 member A
FunctionComponent of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling.
Tissue specificityExpressed in numerous tissues. In normal brain, expressed exclusively in neurons, not in astrocytes. In Alzheimer disease brains, expressed in about half of the activated astrocytes located around classical senile plaques. In Parkinson disease substantia nigra, not detected in melanin-containing neurons nor in activated astrocytes.
Sequence similaritiesBelongs to the PIEZO family.
Cellular localizationEndoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane.
- Information by UniProt