Overview

  • Product name

  • Description

    Rabbit polyclonal to FAM3C/ILEI
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Mouse FAM3C/ILEI (N terminal).

  • General notes

     This product was previously labelled as FAM3C

     

Properties

Applications

Our Abpromise guarantee covers the use of ab56065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • Function

    May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.
  • Tissue specificity

    Present in most secretory epithelia (at protein level).
  • Sequence similarities

    Belongs to the FAM3 family.
  • Cellular localization

    Secreted. Cytoplasmic vesicle. Cytoplasmic in some cancer cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • Fam3c antibody
    • FAM3C_HUMAN antibody
    • Family with sequence similarity 3 member C antibody
    • GS3786 antibody
    • ILEI antibody
    • Interleukin-like EMT inducer antibody
    • Predicted osteoblast protein antibody
    • Protein FAM3C antibody
    see all

Images

  • Anti-FAM3C/ILEI antibody (ab56065) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Predicted band size: 25 kDa
    Observed band size: 30 kDa
    why is the actual band size different from the predicted?
    Additional bands at: 46 kDa. We are unsure as to the identity of these extra bands.

References

This product has been referenced in:

  • Xia HG  et al. Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death. J Cell Biol 210:705-16 (2015). Read more (PubMed: 26323688) »
  • Chaudhury A  et al. TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol : (2010). Read more (PubMed: 20154680) »
See all 2 Publications for this product

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