Recombinant Anti-FAM83H antibody [EPR12542] (ab176329)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12542] to FAM83H
- Suitable for: WB
- Reacts with: Human
Overview
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Product name
Anti-FAM83H antibody [EPR12542]
See all FAM83H primary antibodies -
Description
Rabbit monoclonal [EPR12542] to FAM83H -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC,IHC-P or IP -
Species reactivity
Reacts with: Human
Does not react with: Mouse, Rat -
Immunogen
Recombinant fragment within Human FAM83H. The exact sequence is proprietary.
Database link: Q6ZRV2 -
Positive control
- HT-1376, Human fetal liver and HeLa lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR12542 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab176329 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | 1/1000 - 1/5000. Predicted molecular weight: 127 kDa. |
Target
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Function
May play a major role in the structural organization and calcification of developing enamel. -
Tissue specificity
Expressed in the tooth follicle. -
Involvement in disease
Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3) [MIM:130900]. AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption. -
Sequence similarities
Belongs to the FAM83 family. - Information by UniProt
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Database links
- Entrez Gene: 286077 Human
- Omim: 611927 Human
- SwissProt: Q6ZRV2 Human
- Unigene: 67776 Human
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Alternative names
- AI3 antibody
- FA83H_HUMAN antibody
- Fam83h antibody
see all
Images
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All lanes : Anti-FAM83H antibody [EPR12542] (ab176329) at 1/1000 dilution
Lane 1 : HT-1376 lysate
Lane 2 : Human fetal liver lysate
Lane 3 : HeLa lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 127 kDa
Datasheets and documents
References (0)
ab176329 has not yet been referenced specifically in any publications.