Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab109585 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 42 kDa.|
FunctionDNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Involvement in diseaseDefects in FANCF are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
- Information by UniProt
- A730016A17 antibody
- FACF antibody
- FAF antibody
Lane 1 : Anti-FANCF antibody (ab109585) at 0.5 µg/ml
Lane 2 : Anti-FANCF antibody (ab109585) at 1 mg/ml
Lane 3 : anti-MYC Tag at 1/1000 dilution
Lanes 1 & 3 : HEK293 lysate overexpressing Human FANCF with C-terminal MYC and DYKDDDDK tags
Lane 2 : HEK293 lysate, mock-transfected
Lysates/proteins at 10 µg per lane.
Developed using the ECL technique.
Predicted band size: 42 kDa
Exposure time: 1 hour
ab109585 has not yet been referenced specifically in any publications.