Anti-FANCM antibody (ab167214)
Key features and details
- Mouse polyclonal to FANCM
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-FANCM antibody -
Description
Mouse polyclonal to FANCM -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human
Does not react with: Arabidopsis thaliana -
Immunogen
Recombinant full length protein corresponding to amino acids 1-669 of Human FANCM (AAH36056.1, UniProt ID: Q8IYD8-2).
-
Positive control
- Recombinant Human FANCM protein (ab132334) can be used as a positive control in WB. Lysate from 293T cells transfected with FANCM; HeLa cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab167214 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 76 kDa.
|
|
ICC/IF |
Use a concentration of 10 µg/ml.
|
Notes |
---|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 76 kDa. |
ICC/IF
Use a concentration of 10 µg/ml. |
Target
-
Relevance
FANCM is an ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. It binds to ssDNA but not to dsDNA. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 57697 Human
- Omim: 609644 Human
- SwissProt: Q8IYD8 Human
-
Alternative names
- ATP-dependent RNA helicase FANCM antibody
- FAAP250 antibody
- Fanconi anemia group M protein antibody
see all
Images
Protocols
Datasheets and documents
-
Datasheet download
References (0)
ab167214 has not yet been referenced specifically in any publications.