Anti-Fas Ligand antibody [MFL3] - Low endotoxin, Azide free (ab171253)
Key features and details
- Armenian hamster monoclonal [MFL3] to Fas Ligand - Low endotoxin, Azide free
- Isotype: IgG
Related conjugates and formulations
Overview
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Product name
Anti-Fas Ligand antibody [MFL3] - Low endotoxin, Azide free
See all Fas Ligand primary antibodies -
Description
Armenian hamster monoclonal [MFL3] to Fas Ligand - Low endotoxin, Azide free -
Host species
Armenian hamster -
Immunogen
The details of the immunogen for this antibody are not available.
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General notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Constituent: PBS
Aqueous buffer, no sodium azide. -
Carrier free
Yes -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
MFL3 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Target
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Function
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. -
Involvement in disease
Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Post-translational
modificationsN-glycosylated.
The soluble form derives from the membrane form by proteolytic processing. -
Cellular localization
Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface. - Information by UniProt
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Alternative names
- ALPS1B antibody
- Apoptosis (APO 1) antigen ligand 1 antibody
- Apoptosis antigen ligand 1 antibody
see all
Datasheets and documents
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Datasheet download
References (0)
ab171253 has not yet been referenced specifically in any publications.