Anti-FAT4 antibody (ab130076)
Key features and details
- Rabbit polyclonal to FAT4
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
Overview
-
Product name
Anti-FAT4 antibody -
Description
Rabbit polyclonal to FAT4 -
Host species
Rabbit -
Tested Applications & Species
Application Species WB Recombinant fragment -
Immunogen
Synthetic peptide conjugated to KLH corresponding to a region within Human FAT4 (SwissProt Q6V0I7).
-
Positive control
- recombinant FAT4 protein
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.05% Sodium azide
Constituents: 74% Tris buffered saline, 25% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab130076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
---|---|
WB |
Recombinant fragment
|
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 543 kDa).
|
Notes |
---|
WB
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 543 kDa). |
Target
-
Function
May function in the regulation of planar cell polarity (By similarity). Cadherins are cell-cell interaction molecules. -
Tissue specificity
Widely expressed. Expressed in fetal brain, infant brain, brain tumor and colorectal cancer. -
Sequence similarities
Contains 34 cadherin domains.
Contains 6 EGF-like domains.
Contains 2 laminin G-like domains. -
Cellular localization
Membrane. In the kidney, localizes to primary cilia. - Information by UniProt
-
Alternative names
- Cadherin family member 14 antibody
- Cadherin related family member 11 antibody
- CDHF14 antibody
see all
Images
References (4)
ab130076 has been referenced in 4 publications.
- Malgundkar SH et al. FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and ß-catenin activity in ovarian cancer. BMC Cancer 20:374 (2020). PubMed: 32366234
- Che X et al. FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway. Am J Transl Res 11:2784-2800 (2019). PubMed: 31217854
- Li SY et al. Down-regulated long non-coding RNA RNAZFHX4-AS1 suppresses invasion and migration of breast cancer cells via FAT4-dependent Hippo signaling pathway. Cancer Gene Ther N/A:N/A (2018). PubMed: 30546116
- Ma L et al. Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells. Cancer Biol Ther 17:36-47 (2016). WB ; Human . PubMed: 26575609