Key features and details
- Rabbit polyclonal to FAT/FAT1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-FAT/FAT1 antibody
See all FAT/FAT1 primary antibodies
DescriptionRabbit polyclonal to FAT/FAT1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human FAT/FAT1 (internal sequence). Gene Accession: NP_005236.
Database link: Q14517
- Human thyroid cancer tissue.
This product was previously labelled as FAT
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198892 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
FunctionPlays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
Tissue specificityExpressed in many epithelial and some endothelial and smooth muscle cells.
Sequence similaritiesContains 33 cadherin domains.
Contains 5 EGF-like domains.
Contains 1 laminin G-like domain.
DomainA PTB-like motif (DNXYH sequence) is required for the targeting to the leading edge. This motif represents a minimal protein-protein interaction core motif that is not regulated by tyrosine phosphorylation.
modificationsUndergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus.
Cellular localizationCell membrane. Nucleus. Cytoplasm > perinuclear region.
- Information by UniProt
- Cadherin family member 7 antibody
- Cadherin family member 7 precursor antibody
- Cadherin ME5 antibody
ab198892 has not yet been referenced specifically in any publications.