Fatostatin, SREBP (Sterol regulatory binding protein) transcription factors activation. (ab141490)

Overview

  • Product name

    Fatostatin, SREBP (Sterol regulatory binding protein) transcription factors activation.
  • Description

    Inhibitor of SREBP (Sterol regulatory binding protein) transcription factors activation.
  • Biological description

    Cell-permeable. Inhibits activation of SREBP (Sterol regulatory binding protein) transcription factors. Blocks lipid biosynthesis and accumulation. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    298197-04-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kamisuki S  et al. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. J Med Chem 54:4923-7 (2011). Read more (PubMed: 21561152) »
  • Kamisuki S  et al. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chem Biol 16:882-92 (2009). Read more (PubMed: 19716478) »
  • Choi Y  et al. Identification of bioactive molecules by adipogenesis profiling of organic compounds. J Biol Chem 278:7320-4 (2003). Read more (PubMed: 12496288) »

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