Anti-FBP1 antibody (ab196556)
Key features and details
- Rabbit polyclonal to FBP1
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-FBP1 antibody
See all FBP1 primary antibodies -
Description
Rabbit polyclonal to FBP1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Recombinant full length protein corresponding to Human FBP1.
Database link: P09467 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab196556 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 37 kDa.
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ICC/IF |
1/50 - 1/200.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 37 kDa. |
ICC/IF
1/50 - 1/200. |
Target
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Pathway
Carbohydrate biosynthesis; gluconeogenesis. -
Involvement in disease
Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children. -
Sequence similarities
Belongs to the FBPase class 1 family. - Information by UniProt
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Database links
- Entrez Gene: 2203 Human
- Entrez Gene: 14121 Mouse
- Entrez Gene: 24362 Rat
- Omim: 611570 Human
- SwissProt: P09467 Human
- SwissProt: Q9QXD6 Mouse
- SwissProt: P19112 Rat
- Unigene: 494496 Human
see all -
Alternative names
- 6-bisphosphatase 1 antibody
- 6-bisphosphate 1-phosphohydrolase 1 antibody
- D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody
see all
Images
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All lanes : Anti-FBP1 antibody (ab196556) at 1/500 dilution
Lane 1 : THP1 cell extract
Lane 2 : Mouse kidney extract
Lane 3 : Mouse liver extract
Predicted band size: 37 kDa -
Immunofluorescence analysis of MCF7 cells, labeling FBP1 (green) with ab196556 at 1/50 dilution. Lower panel shows DAPI for nuclear staining (blue).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab196556 has been referenced in 1 publication.
- Li H et al. Fructose-1,6-bisphosphatase-1 decrease may promote carcinogenesis and chemoresistance in cervical cancer. Mol Med Rep 16:8563-8571 (2017). PubMed: 28990097