Overview

  • Product name
  • Description
    Rabbit polyclonal to FBP1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant full length protein corresponding to Human FBP1.
    Database link: P09467

  • Positive control
    • THP1, mouse kidney and liver extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab196556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 37 kDa.
ICC/IF 1/50 - 1/200.

Target

  • Pathway
    Carbohydrate biosynthesis; gluconeogenesis.
  • Involvement in disease
    Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.
  • Sequence similarities
    Belongs to the FBPase class 1 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 6-bisphosphatase 1 antibody
    • 6-bisphosphate 1-phosphohydrolase 1 antibody
    • D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody
    • D-fructose-1 antibody
    • EC 3.1.3.11 antibody
    • F16P1_HUMAN antibody
    • FBP antibody
    • FBP 1 antibody
    • FBP1 antibody
    • FBPase 1 antibody
    • Fructose 1 6 bisphosphatase 1 antibody
    • Fructose bisphosphatase 1 antibody
    • Fructose-1 antibody
    • Growth inhibiting protein 17 antibody
    • Liver fructose bisphosphatase antibody
    see all

Images

  • All lanes : Anti-FBP1 antibody (ab196556) at 1/500 dilution

    Lane 1 : THP1 cell extract
    Lane 2 : Mouse kidney extract
    Lane 3 : Mouse liver extract

    Predicted band size: 37 kDa

  • Immunofluorescence analysis of MCF7 cells, labeling FBP1 (green) with ab196556 at 1/50 dilution. Lower panel shows DAPI for nuclear staining (blue).

References

ab196556 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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