Overview

Description

  • Nature

    Synthetic
  • Amino Acid Sequence
    • Sequence

      C-NSKTKTQYFHQEK

Associated products

Specifications

Our Abpromise guarantee covers the use of ab131394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Fbx32 antibody (ab92281)

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • Reconstitution
    Resuspend in water or in neutral buffer

General Info

  • Alternative names

    • 4833442G10Rik
    • AI430017
    • Atrogin 1
    • Atrogin-1
    • ATROGIN1
    • Atrophy gene 1
    • F box only protein 32
    • F-box only protein 32
    • F-box protein 32
    • FBX32_HUMAN
    • fbxo25
    • FBXO32
    • FLJ32424
    • MAFbx
    • MGC108443
    • MGC137646
    • MGC33610
    • Muscle atrophy F box
    • Muscle atrophy F box protein
    • Muscle atrophy F-box protein
    see all
  • Function

    Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
  • Tissue specificity

    Specifically expressed in cardiac and skeletal muscle.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 F-box domain.
  • Information by UniProt

References

ab131394 has not yet been referenced specifically in any publications.

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