For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to FBXO11
Predicted to work with:
Synthetic peptide, derived from an internal sequence of FBXO11 (UniProt ID: Q86XK2).
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Constituent: Whole serum
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/2000. Predicted molecular weight: 104 kDa.
Use at an assay dependent concentration.
1/100 - 1/1000.
Substrate recognition component of the a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of TP53.
Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.
Protein modification; protein ubiquitination.
Contains 1 F-box domain.
Contains 19 PbH1 repeats. Contains 1 UBR-type zinc finger.
Information by UniProt
F box only protein 11 antibody
F box protein 11 antibody
F-box only protein 11 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"