Key features and details
- Potent mitochondrial oxidative phosphorylation uncoupler
- CAS Number: 370-86-5
- Supplied in DMSO (50 mM)
- Form / State: Liquid
- Source: Synthetic
Product nameFCCP, mitochondrial oxidative phosphorylation uncoupler (DMSO solution)
DescriptionPotent mitochondrial oxidative phosphorylation uncoupler
Potent mitochondrial oxidative phosphorylation uncoupler (IC50 = 20 nM). Disrupts ATP synthesis by transporting protons across mitochondrial inner membranes. Depolarises mitochondrial membrane potential.
Chemical nameCarbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
Storage instructionsShipped at Room Temperature. Store at -20°C long term.
Solubility overviewSupplied in DMSO (50 mM)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab147482 has not yet been referenced specifically in any publications.