Anti-FCGBP antibody (ab121202)
Key features and details
- Rabbit polyclonal to FCGBP
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-FCGBP antibody
See all FCGBP primary antibodies -
Description
Rabbit polyclonal to FCGBP -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence, corresponding to internal sequence amino acids 289-417 of Human FCGBP.
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Positive control
- U 2 OS cells; Human rectum tissue.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab121202 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 1 - 4 µg/ml. using PFA/Triton X-100 Fixation/Permeabilization. | |
| IHC-P | 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa. -
Tissue specificity
Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level). -
Sequence similarities
Contains 12 TIL (trypsin inhibitory-like) domains.
Contains 13 VWFD domains. -
Domain
The N-terminal IgGFc-binding region is primate-specific. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 8857 Human
- SwissProt: Q9Y6R7 Human
- Unigene: 111732 Human
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Alternative names
- Fc fragment of IgG binding protein antibody
- FC(GAMMA)BP antibody
- Fcgamma-binding protein antigen antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FCGBP antibody (ab121202)ab121202 at 1/200 dilution staining FCGBP in Paraffin-embedded Human rectum tissue by Immunohistochemistry.
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Immunocytochemistry/ Immunofluorescence - Anti-FCGBP antibody (ab121202)ab121202 at 4 µg/ml staining FCGBP in PFA/Triton X-100 fixed/permeabilized U 2 OS cells by Immunofluorescence (green).
Protocols
Datasheets and documents
References (1)
ab121202 has been referenced in 1 publication.
- Gäbel G et al. Molecular Fingerprint for Terminal Abdominal Aortic Aneurysm Disease. J Am Heart Assoc 6:N/A (2017). PubMed: 29191809
