Overview

  • Product name

  • Description

    Rabbit polyclonal to FCRL5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human FCRL5 aa 215-260. The exact sequence is proprietary.
    Sequence:

    LSLERS DVPLRFRFFR DDQTLGLGWS LSPNFQITAM WSKDSGFYWC


    Database link: Q96RD9

  • Positive control

    • Jurkat, PC12 and sp2/0 whole cell lysates.
  • General notes

     This product was previously labelled as IRTA2

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purity is > 95% (by SDS-PAGE).
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab201105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 106 kDa.

Target

  • Function

    May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
  • Tissue specificity

    Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B cells and down-regulated in germinal center cells (at protein level).
  • Involvement in disease

    Note=A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32).
  • Sequence similarities

    Contains 8 Ig-like C2-type (immunoglobulin-like) domains.
  • Domain

    Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM).
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BXMAS1 antibody
    • CD307 antigen antibody
    • CD307e antibody
    • Fc receptor homolog 5 antibody
    • Fc receptor like 5 antibody
    • Fc receptor-like protein 5 antibody
    • FcR-like protein 5 antibody
    • FcRH5 antibody
    • FcRL5 antibody
    • FCRL5_HUMAN antibody
    • Immune receptor translocation-associated protein 2 antibody
    • Immunoglobulin receptor translocation associated gene 2 protein antibody
    • Immunoglobulin superfamily receptor translocation associated gene 2 protein antibody
    • IRTA2 antibody
    • UNQ503/PRO820 antibody
    see all

Images

  • All lanes : Anti-FCRL5 antibody (ab201105)

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : PC12 whole cell lysate
    Lane 3 : sp2/0 whole cell lysate

    Predicted band size: 106 kDa

References

ab201105 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab201105.
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