Overview

  • Product name

  • Description

    Rabbit polyclonal to FDCSP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    amino acids 28-81 (KRSISDSDEL ASGFFVFPYP YPFRPLPPIP FPRFPWFRRN FPIPIPESAP TTPL) of Human FDCSP.

  • Positive control

    • Human tonsil tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Can bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.
  • Tissue specificity

    Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C4orf7 antibody
    • FDC secreted protein antibody
    • FDC-SP antibody
    • FDCSP antibody
    • FDSCP_HUMAN antibody
    • Follicular dendritic cell secreted peptide antibody
    • Follicular dendritic cell secreted protein antibody
    see all

Images

  • ab121420, at a 1/100 dilution, staining FDCSP in paraffin-embedded Human tonsil tissue by Immunohistochemistry.
  • Immunohistochemical staining of Human tonsil shows strong cytoplasmic positivity in squamous epithelial cells using ab121420

References

This product has been referenced in:

  • Kinchen J  et al. Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. Cell 175:372-386.e17 (2018). Read more (PubMed: 30270042) »
See 1 Publication for this product

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