Overview

  • Product name
    Anti-FDFT1 antibody [EPR4626]
    See all FDFT1 primary antibodies
  • Description
    Rabbit monoclonal [EPR4626] to FDFT1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, WB, IPmore details
    Unsuitable for: Flow Cyt or IHC-P
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human FDFT1. The exact sequence is proprietary.

  • Positive control
    • Fetal liver, HepG2, Molt-4, and SH-SY5Y lysates
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab109723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/100.
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt or IHC-P.

    • Target

    • Pathway
      Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
    • Sequence similarities
      Belongs to the phytoene/squalene synthase family.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
      • Alternative names
        • DGPT antibody
        • ERG9 antibody
        • Farnesyl diphosphate farnesyltransferase antibody
        • Farnesyl-diphosphate farnesyltransferase antibody
        • FDFT_HUMAN antibody
        • FDFT1 antibody
        • FPP:FPP farnesyltransferase antibody
        • SQS antibody
        • Squalene synthase antibody
        • Squalene synthetase antibody
        • SS antibody
        see all

      Images

      • Western blot - Anti-FDFT1 antibody [EPR4626] (ab109723)
        Western blot - Anti-FDFT1 antibody [EPR4626] (ab109723)
        All lanes : Anti-FDFT1 antibody [EPR4626] (ab109723) at 1/1000 dilution

        Lane 1 : Fetal liver lysate
        Lane 2 : HepG2 lysate
        Lane 3 : Molt-4 lysate
        Lane 4 : SH-SY5Y lysates

        Lysates/proteins at 10 µg per lane.

        Secondary
        All lanes : Standard HRP labelled goat anti-rabbit at 1/2000 dilution

        Predicted band size: 48 kDa

      References

      This product has been referenced in:
      • Shimada K  et al. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat Chem Biol 12:497-503 (2016). WB . Read more (PubMed: 27159577) »

      See 1 Publication for this product

      Publishing research using ab109723? Please let us know so that we can cite the reference in this datasheet.

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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