Recombinant
RabMAb

Recombinant Anti-FECH antibody [EPR8312] (ab137042)

Overview

  • Product name

    Anti-FECH antibody [EPR8312]
    See all FECH primary antibodies
  • Description

    Rabbit monoclonal [EPR8312] to FECH
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human FECH (UniProt ID: P22830)

  • Positive control

    • Human fetal liver and K562 lysates
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab137042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Catalyzes the ferrous insertion into protoporphyrin IX.
    • Pathway

      Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.
    • Involvement in disease

      Erythropoietic protoporphyria (EPP) [MIM:177000]: A form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. Erythropoietic protoporphyria is marked by excessive protoporphyrin in erythrocytes, plasma, liver and feces, and by widely varying photosensitive skin changes ranging from a burning or pruritic sensation to erythema, edema and wheals. Note=The disease is caused by mutations affecting the gene represented in this entry.
    • Sequence similarities

      Belongs to the ferrochelatase family.
    • Cellular localization

      Mitochondrion inner membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • EPP antibody
      • FCE antibody
      • Fch antibody
      • Fcl antibody
      • fech antibody
      • Ferrochelatase (protoporphyria) antibody
      • Ferrochelatase antibody
      • Ferrochelatase mitochondrial antibody
      • Heme synthase antibody
      • Heme synthetase antibody
      • HEMH_HUMAN antibody
      • mitochondrial antibody
      • Protoheme ferro lyase antibody
      • Protoheme ferro-lyase antibody
      • Protoporphyria antibody
      see all

    Images

    • All lanes : Anti-FECH antibody [EPR8312] (ab137042) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : K562 cell lysate

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 48 kDa

    References

    ab137042 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab137042.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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