Product nameFenoldopam hydrochloride, D1-like dopamine receptor partial agonist
DescriptionSelective D1-like dopamine receptor partial agonist. Vasodilator in vivo. α2-adrenoceptor antagonist in vitro.
- 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride
- SK & F82526
Chemical name6-Chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Chen Y et al. Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis. Hypertension 62:927-33 (2013). Read more (PubMed: 24019399) »
- Grenader A & Healy DP Fenoldopam is a partial agonist at dopamine-1 (DA1) receptors in LLC-PK1 cells. J Pharmacol Exp Ther 258:193-8 (1991). Read more (PubMed: 1677038) »
- Nichols AJ et al. The pharmacology of fenoldopam. Am J Hypertens 3:116S-119S (1990). Read more (PubMed: 1974439) »
- Ohlstein EH et al. The DA1 receptor agonist fenoldopam (SK & F 82526) is also an alpha 2-adrenoceptor antagonist. Eur J Pharmacol 118:321-9 (1985). Read more (PubMed: 2867915) »
- Hahn RA et al. Characterization of the peripheral and central effects of SK&F 82526, a novel dopamine receptor agonist. J Pharmacol Exp Ther 223:305-13 (1982). Read more (PubMed: 6127401) »
- Sibley DR et al. Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors. Life Sci 31:637-45 (1982). Read more (PubMed: 6127585) »