Fenoprofen calcium dihydrate, antiarthritic agent (ab142655)

Overview

  • Product name

    Fenoprofen calcium dihydrate, antiarthritic agent
  • Description

    NSAID and antiarthritic agent
  • Biological description

    NSAID and antiarthritic agent. Blocks sodium-coupled monocarboxylate transporter as a non-transportable substrate. Inhibits proliferation in cancer cell lines. Anti-inflammatory and antinociceptive effects in vivo. Orally active.
  • Purity

    > 97%
  • CAS Number

    53746-45-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Calcium 2-(3-phenoxyphenyl)propanoate dihydrate
  • Molecular weight

    558.64
  • Molecular formula

    C30H26CaO6.2H2O
  • PubChem identifier

    64747
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)[O-].CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)[O-].O.O.[Ca+2]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Ganapathy V  et al. Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. AAPS J 10:193-9 (2008). Read more (PubMed: 18446519) »
  • Barbaric M  et al. Synthesis and in vitro antitumor effect of diclofenac and fenoprofen thiolated and nonthiolated polyaspartamide-drug conjugates. Eur J Med Chem 42:20-9 (2007). Read more (PubMed: 17010482) »
  • Itagaki S  et al. Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8). Pharm Res 23:1209-16 (2006). Read more (PubMed: 16729224) »
  • Phadke K  et al. Effects of various anti-inflammatory drugs on type II collagen-induced arthritis in rats. Clin Exp Immunol 47:579-86 (1982). Read more (PubMed: 6979443) »

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