Overview

  • Product name
    Anti-Ferredoxin Reductase antibody
    See all Ferredoxin Reductase primary antibodies
  • Description
    Rabbit polyclonal to Ferredoxin Reductase
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment of Human Ferredoxin Reductase protein, purified from E. coli.

  • Positive control
    • Human Adrenal and Pancreas tissues.
  • General notes
    Aliquots are stable for at least 12 months at -20°C.

Properties

Applications

Our Abpromise guarantee covers the use of ab122900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/3000. Predicted molecular weight: 54 kDa.
IHC-P 1/200.
IP Use at an assay dependent concentration.

Target

  • Function
    Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
  • Pathway
    Steroid metabolism; cholesterol metabolism.
  • Sequence similarities
    Belongs to the ferredoxin--NADP reductase type 1 family.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adrenodoxin reductase antibody
    • ADRO_HUMAN antibody
    • ADXR antibody
    • AR antibody
    • FDXR antibody
    • Ferredoxin NADP(+) reductase antibody
    • Ferredoxin reductase antibody
    • Ferredoxin--NADP(+) reductase antibody
    • mitochondrial antibody
    • NADPH adrenodoxin oxidoreductase mitochondrial antibody
    • NADPH:adrenodoxin oxidoreductase antibody
    see all

Images

  • ab122900, at 1/200 dilution, staining Ferredoxin Reductase in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
  • ab122900, at 1/200 dilution, staining Ferredoxin Reductase in Formalin-fixed, Paraffin-embedded Human Pancreas tissue by Immunohistochemistry.

References

This product has been referenced in:
  • Zhang MF  et al. Differentiation Model Establishment and Differentiation-Related Protein Screening in Primary Cultured Human Sebocytes. Biomed Res Int 2018:7174561 (2018). Read more (PubMed: 29850553) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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