Key features and details
- Goat polyclonal to Ferritin
- Suitable for: RIA, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Ferritin antibody
See all Ferritin primary antibodies
DescriptionGoat polyclonal to Ferritin
Specificityab33574 recognises Human Liver Ferritin 100%; Human Spleen Ferritin 100%; Human Heart Ferritin < 1%.
Tested applicationsSuitable for: RIA, ELISAmore details
Species reactivityReacts with: Human
Full length native protein (purified) corresponding to Human Ferritin. Full length native protein (purified): Human liver ferritin
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Concentration information loading...
PurityProtein G purified
Purification notesab33574 is purified by affinity chromatography. No contaminants detected. Single band by SDS-PAGE, IEP, and/or RID.
Our Abpromise guarantee covers the use of ab33574 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|RIA||Use at an assay dependent dilution.|
|ELISA||Use at an assay dependent dilution.|
FunctionStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Sequence similaritiesBelongs to the ferritin family.
Contains 1 ferritin-like diiron domain.
- Information by UniProt
FormSubunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab33574 has been referenced in 1 publication.
- Bleicher AV et al. A sandwich enzyme-linked immunosorbent assay for the quantitation of human plasma ferritin. MethodsX 5:648-651 (2018). PubMed: 29998067