Overview

  • Product name

  • Description

    Goat polyclonal to Ferritin
  • Host species

    Goat
  • Specificity

    ab33574 recognises Human Liver Ferritin 100%; Human Spleen Ferritin 100%; Human Heart Ferritin < 1%.
  • Tested applications

    Suitable for: RIA, ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human Ferritin. Full length native protein (purified): Human liver ferritin

Properties

Applications

Our Abpromise guarantee covers the use of ab33574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • Function

    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
  • Sequence similarities

    Belongs to the ferritin family.
    Contains 1 ferritin-like diiron domain.
  • Information by UniProt
  • Database links

  • Form

    Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
  • Alternative names

    • Cell proliferation-inducing gene 15 protein antibody
    • Ferritin H subunit antibody
    • Ferritin heavy chain antibody
    • Ferritin heavy polypeptide 1 antibody
    • Ferritin L chain antibody
    • Ferritin L subunit antibody
    • Ferritin light chain antibody
    • Ferritin light polypeptide antibody
    • ferritin light polypeptide like 3 antibody
    • Ferritin, heavy polypeptide antibody
    • FHC antibody
    • FRIH_HUMAN antibody
    • FTH antibody
    • FTH1 antibody
    • FTHL6 antibody
    • FTL antibody
    • MGC104426 antibody
    • PIG15 antibody
    • PLIF antibody
    • Proliferation inducing protein 15 antibody
    see all

References

This product has been referenced in:

  • Bleicher AV  et al. A sandwich enzyme-linked immunosorbent assay for the quantitation of human plasma ferritin. MethodsX 5:648-651 (2018). Read more (PubMed: 29998067) »
See 1 Publication for this product

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