Product nameAnti-Ferritin antibody (Biotin)
See all Ferritin primary antibodies
DescriptionRabbit polyclonal to Ferritin (Biotin)
Tested applicationsSuitable for: WB, ELISA, RIAmore details
Species reactivityReacts with: Mouse
Full length native protein (purified) corresponding to Mouse Ferritin. Full length native protein, purified from Mouse liver
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab86247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.|
|ELISA||Use at an assay dependent dilution.|
|RIA||Use at an assay dependent dilution.|
FunctionStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Sequence similaritiesBelongs to the ferritin family.
Contains 1 ferritin-like diiron domain.
- Information by UniProt
FormSubunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
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This product has been referenced in:
- Guerrero-Hue M et al. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. FASEB J N/A:fj201900077R (2019). Read more (PubMed: 31034781) »
- Rubio-Navarro A et al. CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles. Theranostics 6:896-914 (2016). IHC . Read more (PubMed: 27162559) »