Overview

  • Product name

    Anti-Ferritin antibody (Biotin)
    See all Ferritin primary antibodies
  • Description

    Rabbit polyclonal to Ferritin (Biotin)
  • Host species

    Rabbit
  • Conjugation

    Biotin
  • Tested applications

    Suitable for: WB, ELISA, RIAmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Full length native protein (purified) corresponding to Mouse Ferritin. Full length native protein, purified from Mouse liver

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab86247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • Function

    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
  • Sequence similarities

    Belongs to the ferritin family.
    Contains 1 ferritin-like diiron domain.
  • Information by UniProt
  • Database links

  • Form

    Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
  • Alternative names

    • Cell proliferation-inducing gene 15 protein antibody
    • Ferritin H subunit antibody
    • Ferritin heavy chain antibody
    • Ferritin heavy polypeptide 1 antibody
    • Ferritin L chain antibody
    • Ferritin L subunit antibody
    • Ferritin light chain antibody
    • Ferritin light polypeptide antibody
    • ferritin light polypeptide like 3 antibody
    • Ferritin, heavy polypeptide antibody
    • FHC antibody
    • FRIH_HUMAN antibody
    • FTH antibody
    • FTH1 antibody
    • FTHL6 antibody
    • FTL antibody
    • MGC104426 antibody
    • PIG15 antibody
    • PLIF antibody
    • Proliferation inducing protein 15 antibody
    see all

References

This product has been referenced in:

  • Guerrero-Hue M  et al. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. FASEB J N/A:fj201900077R (2019). Read more (PubMed: 31034781) »
  • Rubio-Navarro A  et al. CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles. Theranostics 6:896-914 (2016). IHC . Read more (PubMed: 27162559) »
See all 2 Publications for this product

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