Full length protein corresponding to Human Ferritin. Human spleen ferritin. Database link: P02794
Shipped at 4°C. Store at +4°C.
pH: 7.20 Preservative: 0.01% Gentamicin sulphate
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ab31996 was prepared from monospecific antiserum, delipidated and defibrinated. Assayed by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified human spleen ferritin.
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Belongs to the ferritin family. Contains 1 ferritin-like diiron domain.
Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
Cell proliferation-inducing gene 15 protein antibody